Bupropion (R)-Isomer Tartrate CAS 437723-96-1 (free base)
| CAS No. | 437723-96-1 (free base) |
| Molecular Formula | C13H18ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Bupropion (R)-Isomer Tartrate (CAS 437723-96-1 (free base)), molecular formula C13H18ClNOC4H6O6 and molecular weight 389.83 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Bupropion (R)-Isomer Tartrate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 389.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18ClNO C4H6O6 |
| Molecular Weight | 389.83 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bupropion Standards
- Bupropion Impurity 72 (CAS 102141-11-7)
- Bupropion Impurity 71 (CAS 102141-12-8)
- Bupropion Impurity 9 (CAS 103175-61-7)
- Bupropion Hydrochloride USP Related Compound B (CAS 1049718-43-5)
- Bupropion Hydrochloride USP Related Compound A (CAS 1049718-72-0)
- Bupropion impurity 67 (CAS 1049974-40-4)
- Bupropion Impurity 17 (CAS 10557-17-2)
- Bupropion Morpholinol Impurity (HCl Salt) (CAS 106083-71-0)
Recommended Standards
- 4-Cyclopropoxybenzaldehyde (CAS 915016-52-3)
- 4-(2,5-Dimethylpyrrolidin-1-yl)morpholine (CAS 6966-91-2)
- Benzyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 363186-06-5)
- Bzl-Gly-Oet (CAS 6436-90-4)
- Ethyl 2,6-dimethylquinoline-3-carboxylate (CAS 892874-63-4)
- tert-Butyl (5-(dimethylphosphoryl)-3-methoxypyridin-2-yl)carbamate (CAS 2903924-68-3)
- 7-Fluorobenzoxazole (CAS 1267061-18-6)
- 1-acetyl-3-(3-amino-2-methylphenyl)imidazolidin-2-one (CAS 1803606-36-1)
- Travoprost Impurity 12 (CAS 39746-01-5)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
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